Early hyperlactatemia predicts pancreatic fistula after surgery

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Early hyperlactatemia predicts pancreatic fistula after surgery

BACKGROUND Postoperative pancreatic fistula (POPF) is a major complication after pancreatic surgery and results from an impaired healing of the pancreatic enteric anastomosis. Whether perioperative hemodynamic fluid management aiming to provide an adequate tissue perfusion could influence the occurrence of POPF is unknown. Serum lactate level is a well-recognized marker of decreased tissue perf...

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Endoscopic ultrasound-guided transmural drainage for pancreatic fistula or pancreatic duct dilatation after pancreatic surgery

Background Endoscopic ultrasound (EUS)-guided drainage is widely used to manage pancreatic pseudocysts. Several studies have reported the use of EUS-guided drainage for pancreatic fistula and stasis of pancreatic juice caused by stricture of the pancreatic duct after pancreatic resection. Methods In total, 262 patients underwent surgery involving pancreatic resection in our hospital from April ...

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Frequency, risk factors, and outcome of hyperlactatemia after cardiac surgery.

STUDY OBJECTIVE To determine the respective frequencies, risk factors, and outcomes of no hyperlactatemia (NHL), immediate hyperlactatemia (IHL), or late hyperlactatemia (LHL) > 3 mmol/L after cardiac surgery. DESIGN Prospective and observational study. SETTING Cardiac surgery ICU in a 130-bed private community nonteaching hospital. PATIENTS Consecutive patients (n = 325) undergoing cardi...

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Hyperlactatemia and Cardiac Surgery.

The normal blood lactate level is 0-2 mmol/L, and a value above 3-5 mmol/L is variably used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from both hypoxic and non-hypoxic mechanisms. The major non-hypoxic mechanism is likely stress-induced accelerated aerobic metabolism, in which elevated lactate results from a mass effect on the lactate/pyruvate equilibriu...

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Risk factors and preventive strategies for post-operative pancreatic fistula after pancreatic surgery: a comprehensive review

BACKGROUND Pancreas surgery has developed into a fairly safe procedure in terms of mortality, but is still hampered by considerable morbidity. Among the most frequent and dreaded complications are the development of a post-operative pancreatic fistula (POPF). The prediction and prevention of POPF remains an area of debate with several questions yet to be firmly addressed with solid answers. M...

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ژورنال

عنوان ژورنال: BMC Anesthesiology

سال: 2015

ISSN: 1471-2253

DOI: 10.1186/s12871-015-0093-x